Procyanidin B2

Abstract

(+) catechin and (-) epicatechin form proanthocyanidins, including procyanidins. Procyanidins can be categorized into A-type and B-type, depending on the nature of the interflavan bonds. B-type procyanidins have a single interflavan bond. A-type procyanidins have not only one interflavan bond, but also a second interflavanoid bond. The most common B-type procyanidins are B1, B2, B3, and B4. Procyanidin B2 (CAS 21906-49-8) is an epicatechin-(4β→8)-epicatechin dimer. Cinnamon, cocoa, and apples contain procyanidin B2.

Recent research indicates that Procyanidin B2 (CAS 21906-49-8) is a protein kinase inhibitor, promoting hair epithelial cell growth and stimulating anagen induction. Furthermore, B2 demonstrates other bioactivities and, therefore, possesses the potential to treat a wide range of diseases, such as diabetes mellitus, atherosclerosis, and non-alcoholic fatty liver disease.

You can find additional procyanidin reference standards here.

Categories: Apple PACs, Cinnamon PACs, Cocoa PACs, Procyanidins (PACs)

Compound Details

CAS	21906-49-8
Molecular Weight	578.52
Chemical Formula	C30H26O12
IUPAC	(2R,3R)-2-(3,4-dihydroxyphenyl)-8-[(2R,3R,4R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-4-yl]-3,4-dihydro-2H-chromene-3,5,7-triol
Synonyms	–
SMILES	C1C(C(OC2=C1C(=CC(=C2C3C(C(OC4=CC(=CC(=C34)O)O)C5=CC(=C(C=C5)O)O)O)O)O)C6=CC(=C(C=C6)O)O)O
Purity	98%+
Storage Temperature	Below -18 degrees C
Storage Conditions	Dry, freezer

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