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Compound Purification & Natural Product Isolation
Planta Analytica purifies compounds from botanical extracts, natural products, and other complex mixtures, using preparative HPLC, flash chromatography, and counter-current separation. We deliver purified isolates with full traceability and documented integrity, from milligram to gram scale.
Who we help
We support organizations purifying both natural and synthetic products across these industries:
Pharmaceutical
Agrochemical
Botanical & nutraceutical
Functional foods & flavors
Research & development teams
The challenge
Purifying a target compound from a botanical extract or complex mixture is rarely straightforward. Minor constituents, polar and labile metabolites, structural isomers, and structurally complex phytochemicals can be difficult to separate with traditional chromatography alone, yet reference standards, regulatory submissions, quality control, and R&D all depend on material of high, documented purity.
Planta Analytica customizes each purification strategy to the compound chemistry, matrix complexity, and intended use.
Our capabilities
Preparative HPLC & flash chromatography
Advanced chromatographic techniques to isolate and refine bioactive compounds with high precision and reproducibility.
Counter-current
separation
Counter-current (centrifugal partition) chromatography for challenging separations beyond traditional chromatography.
Analytical confirmation & Certification
Verified purity with high quality analytics, such as HPLC-UV, MS, NMR (via partner labs), residual solvents, and Karl-Fischer titration. Purity up to 99.9%.
Broad molecular weight range
Tailored to molecular weights between 100–3,000 Dalton and applicable to most classes of organic molecules, including small molecules, peptides, and botanical constituents.
Reference standards expertise
Built on a catalog of nearly 200 unique reference standards and hundreds of completed projects over the past two decades.
Difficult & Unusual
Cases
Experts in highly labile compounds, structural isomers, and extremes of polarity.
How it works
Share what you have
Send us whatever you know through our submission questionnaire.
NDA if needed
We put an NDA in place to protect confidential IP.
Formal quote
You receive a quote; larger projects start with a 1–2 week feasibility study.
PO & shipment
Once we receive your PO, we coordinate shipment to our lab.
LIMS intake
Your sample is reviewed, logged in our LIMS and trackable in your dashboard.
Purification & delivery
We purify, confirm identity and purity, and deliver with a report.
What to send us
- Already extracted or fractionated products
- Synthetic samples
- Raw material, with our support for procurement for the isolation
- Any information you have: chromatogram, feedstock, molecular weight, possible structure
Typical timelines
Routine purifications: typically about 5 business days.
Complex purifications: typically 3–4 weeks.
Specialty projects: lead time determined per project.
Larger projects: typically start with a 1–2 week feasibility study.
Quality
Planta Analytica is not currently ISO or GLP certified or accredited. We strictly follow GLP principles and ISO/IEC 17025 practices, and we are working towards ISO/IEC 17025 accreditation.
What you receive
- Purified compound (isolate), from milligrams to larger scale as needed
- Certificate of purity with supporting analytical data (e.g. HPLC-UV, MS, NMR, residual solvents, Karl-Fischer)
- Full traceability and documented integrity
- Optional structure elucidation report backed with full analytical data
Service supplement: Structure Elucidation
Whether you need to confirm a structure or elucidate a series of polymeric isomers, our structural elucidation experts offer high certainty and short lead times.
Frequently asked questions
Botanical extracts, natural products, and other complex mixtures, both natural and synthetic products. Our workflows cover small molecules, peptides, and botanical constituents in the 100–3,000 Dalton range.
Our workflows routinely achieve ≥99 percent purity, with purity up to 99.9% certified by analytics such as HPLC-UV, MS, and NMR. Achievable purity depends on the compound and matrix.
We offer compound purification from milligram to gram scale, and can scale processes to suit your needs. The right scale depends on the compound and amount; we provide a quote after reviewing your questionnaire.
Yes. We specialize in highly labile compounds, structural isomers, extremes of polarity, minor constituents, and polar and labile metabolites.
Pricing is project dependent. Routine purifications are typically turned around in about 5 business days, more complex purifications typically take 3–4 weeks, and lead times for specialty projects are determined per project. Larger projects usually start with a 1–2 week feasibility study that de-risks the project, estimates its scope, and develops the method.
Yes. If your project involves confidential IP, we can put a non-disclosure agreement in place before you share details.
Yes. Once your sample is received and reviewed, it is entered into our LIMS, and you can track your order in your online client dashboard.
Click “Request a Quote” to complete our service questionnaire, or contact us to talk with a scientist.
Ready to purify your compound?
Partner with Planta Analytica to accelerate discovery, validate reference materials, and support product development.