Withanolide B
CAS: 56973-41-2
CAT: 10663
Abstract
Withanolide B (CAS 56973-41-2) is a steroidal lactone from the withanolide family. It occurs naturally in the roots and leaves of Withania somnifera (L.), commonly known as Ashwagandha or Indian ginseng.
This adaptogenic herb has been a key part of Ayurvedic medicine for centuries. People have traditionally used it to boost vitality, support brain function, and improve resilience to stress. Withanolides are the main active compounds responsible for these benefits.
Withanolide B has attracted scientific interest due to its neuroprotective, antioxidant, and anti-inflammatory properties. For example, research shows it helps inhibit β-amyloid aggregation. This makes it a promising compound for studies on Alzheimer’s disease and other neurodegenerative conditions.(1) In addition, Withanolide B supports cellular protection and contributes to the adaptogenic effects of Ashwagandha by helping regulate stress responses.
As a key marker for standardization, Withanolide B plays an important role in quality control and analysis of Ashwagandha extracts. These extracts are widely used in nutraceuticals, dietary supplements, and herbal medicines. Accurate measurement ensures consistent potency, reliable batches, and regulatory compliance.
Planta Analytica offers high-purity Withanolide B reference standards. They suit HPLC, UPLC, LC-MS, and other advanced analytical methods, as well as pharmacological research and natural product development.
References:
References
Withanoside IV and its active metabolite
Compound Details
| CAS | 56973-41-2 |
|---|---|
| Molecular Weight | 454.6 |
| Chemical Formula | C28H38O5 |
| IUPAC | (1S,2S,4S,5R,10R,11S,14R,15R,18S)-15-[(1S)-1-[(2R)-4,5-dimethyl-6-oxo-2,3-dihydropyran-2-yl]ethyl]-5-hydroxy-10,14-dimethyl-3-oxapentacyclo[9.7.0.02,4.05,10.014,18]octadec-7-en-9-one |
| SMILES | CC1=C(C(=O)O[C@H](C1)[C@@H](C)[C@H]2CC[C@@H]3[C@@]2(CC[C@H]4[C@H]3[C@H]5[C@H](O5)[C@@]6([C@@]4(C(=O)C=CC6)C)O)C)C |
| Purity | 90%+ |
| Storage Temperature | Below -18 degrees C |
| Storage Conditions | Dry, Freezer |
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Products are sold as laboratory reference materials, to be used for diagnostic and in vivo testing. The samples are not certified for veterinary or human use.
