Senecionine

Abstract

Senecionine (CAS 130-01-8) is a pyrrolizidine alkaloid (PA) isolated from the Senecio genus and also found in certain plants of the Jacobea genus. Senecionine can be present in honey made from the nectar of the plant and has become a compound of interest for monitoring Pyrrolizidine alkaloid (PA) content in honey and related products.

PAs are secondary metabolites in plants; about half of these alkaloids exhibit toxicity and carcinogenicity. Pyrrolizidine alkaloids poison grazing animals and domestic livestock through contaminated plants or feed. These alkaloids then poison humans through contaminated food (e.g., grains, honey, and milk), herbal medicine, and supplements. The plant is also toxic to livestock, and considered and undesirable wildflower.

Find the entire collection of pyrrolizidine alkaloids here.

Category: Pyrrolizidine Alkaloids Tag: alkaloid

Compound Details

CAS	130-01-8
Molecular Weight	335.4
Chemical Formula	C18H25NO5
IUPAC	(1R,4Z,6R,7R,17R)-4-ethylidene-7-hydroxy-6,7-dimethyl-2,9-dioxa-14-azatricyclo[9.5.1.014,17]heptadec-11-ene-3,8-dione
Synonyms	Aureine, Senecionin
SMILES	CC=C1CC(C(C(=O)OCC2=CCN3C2C(CC3)OC1=O)(C)O)C
Purity	95%+
Storage Temperature	Below -18 degrees C
Storage Conditions	Dry, freezer

Product Documents

Certificates of Analysis

038-060-001

Safety Data Sheets

MSDS

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$15.50 - $21.00 / milligram

Range (milligram)	Price ($/milligram)
5 - 24 milligram	$21.00 / milligram
25 - 99 milligram	$19.50 / milligram
100 - 249 milligram	$18.00 / milligram
250 - 499 milligram	$16.75 / milligram
500 - 1000 milligram	$15.50 / milligram

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