Ursolic Acid

Abstract

Ursolic acid (CAS 77-52-1) is a pentacyclic triterpenoid identified in the epicuticular waxes of apples and widely found in the peels of fruits, as well as in herbs and spices like rosemary and thyme.

In vitro, ursolic acid inhibits the proliferation of various cancer cell types by inhibiting the STAT3 activation pathway, and may also decrease proliferation of cancer cells and induce apoptosis. Ursolic acid has also been shown to inhibit JNK expression and IL-2 activation of JURKAT leukemic T Cells leading to the reduction in proliferation and T cell activation.

Category: Uncategorized

Compound Details

CAS	77-52-1
Molecular Weight	456.7
Chemical Formula	C30H48O3
IUPAC	(1S,2R,4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
Synonyms	N/A
SMILES	CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1C)C)C(=O)O
Purity	95%+
Storage Temperature	Below -18 degrees C
Storage Conditions	Dry, freezer

Product Documents

Certificates of Analysis

040-174-102

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MSDS

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