Spinosyn A
CAS: 131929-60-7
CAT: 5070
Abstract
Spinosyn A (CAS 131929-60-7) is a macrocyclic lactone insecticide and the principal active component of Spinosad, a leading fermentation-derived biopesticide. It is produced by the soil actinomycete Saccharopolyspora spinosa and is isolated and purified as a high-purity reference standard from Spinosad technical agrochemical material.
Spinosyn A has become a key active ingredient in modern crop protection strategies. It exhibits potent insecticidal activity by both contact and ingestion against a broad spectrum of economically important pests across multiple orders, including Lepidoptera, Diptera, Thysanoptera, Coleoptera, Orthoptera, Hymenoptera, and many others. Its overall efficacy and protective performance can vary depending on the target insect species and developmental life stage.
The mode of action of spinosyns is unique among insecticides. Spinosyn A acts primarily as an allosteric modulator of nicotinic acetylcholine receptors (nAChRs) in the insect central nervous system, causing hyperexcitation, disrupted neurotransmission, involuntary muscle contractions, paralysis, and death. This novel neural mechanism has proven highly valuable for resistance management programs, as Spinosad has demonstrated no cross-resistance to other known classes of insecticides.
In addition to its field performance, Spinosyn A serves as a critical marker compound for the standardization, quality control, and analytical verification of Spinosad-based technical concentrates and formulated biopesticide products. Precise quantification of Spinosyn A content is essential for agrochemical manufacturers and formulators to ensure batch-to-batch consistency, potency, regulatory compliance, and reliable performance in crop protection, horticulture, and integrated pest management (IPM) applications.
Planta Analytica supplies high-purity Spinosyn A reference standards isolated from Spinosad technical material. These standards are used throughout the agrochemical industry for method development, validation, residue analysis, batch release testing, and quality assurance. You can follow this link for our entire collection of agrochemical reference standards.
References
Withanoside IV and its active metabolite
Compound Details
| CAS | 131929-60-7 |
|---|---|
| Molecular Weight | 732.0 g/mol |
| Chemical Formula | C₄₁H₆₅NO₁₀ |
| IUPAC | (1S,2R,5S,7R,9R,10S,14R,15S,19S)-15-[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy-19-ethyl-14-methyl-7-[(2R,3R,4R,5S,6S)-3,4,5-trimethoxy-6-methyloxan-2-yl]oxy-20-oxatetracyclo[10.10.0.02,10.05,9]docosa-3,11-diene-13,21-dione |
| Synonyms | Lepicidin A |
| SMILES | CCC1CCCC(C(C(=O)C2=CC3C4CC(CC4C=CC3C2CC(=O)O1)OC5C(C(C(C(O5)C)OC)OC)OC)C)OC6CCC(C(O6)C)N(C)C |
| Purity | 95%+ |
| Storage Temperature | Below −18°C |
| Storage Conditions | Dry, freezer |
Product Documents
PRICE ON REQUEST
Technical Support
Product information is from published literature. Due to the nature of scientific experimentation, results or specific product application may vary (e.g., selectivity, detector response). If you have questions about the product, its application, and associated analytics, please contact our technical support team.
Product Use Disclaimer
Products are sold as laboratory reference materials, to be used for diagnostic and in vivo testing. The samples are not certified for veterinary or human use.
Related Products
