Oleandrin

Abstract

Nerium oleander (oleander) is well-known for its biological activities. Nerium contains several toxic compounds, and it has historically been considered a poisonous plant. Oleandrin (CAS 465-16-7) is a lipid-soluble steroidal glycoside commonly isolated from N. oleander and is the major active component in this plant. Oleandrin demonstrates a wide spectrum of beneficial biological and pharmacological activities. It is used to treat various diseases, including congestive heart failure, abscesses, asthma, eczema, epilepsy, herpes, leprosy, malaria, ringworm, scabies, indigestion, strokes, and neurodegenerative diseases. Recent research has shown that oleandrin is also effective against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

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Compound Details

CAS

465-16-7

Molecular Weight

576.7

Chemical Formula

C32H48O9

IUPAC

[(3S,5R,8R,9S,10S,13R,14S,16S,17R)-14-hydroxy-3-[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-10,13-dimethyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-16-yl] acetate

Synonyms

5β,20(22)-Cardenolide-3β, Corrigen, Foliandrin, Folinerin, Neriol, Neriolin, Neriostene

SMILES

CC1C(C(CC(O1)OC2CCC3(C(C2)CCC4C3CCC5(C4(CC(C5C6=CC(=O)OC6)OC(=O)C)O)C)C)OC)O

Purity

95%+

Storage Temperature

Below -18 degrees C

Storage Conditions

Dry, freezer

Product Documents

Certificates of Analysis

Safety Data Sheets

Product Use Disclaimer

Products are sold as laboratory reference materials, to be used for diagnostic and in vivo testing. The samples are not certified for veterinary or human use. 

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Product information is from published literature. Due to the nature of scientific experimentation, results or specific product application may vary (e.g., selectivity, detector response). If you have questions about the product, its application, and associated analytics, please contact our technical support team.

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