Curcumin
CAS: 458-37-7
CAT: 9683
Abstract
Curcumin (CAS 458-37-7) is a major curcuminoid found in Curcuma longa, the plant source of turmeric. It belongs to the diarylheptanoid family and is known as diferuloylmethane. The structure consists of two ferulic acid units linked by a seven-carbon chain. This unique configuration gives curcumin its bright yellow color and broad pharmacological activity.
Researchers highly value curcumin for its strong anti-inflammatory and antioxidant effects. It serves as an important reference standard in studies on arthritis, osteoarthritis, and other chronic inflammatory conditions. Curcumin modulates key targets such as NF-κB, COX-2, and iNOS. It also inhibits histone acetyltransferase activity, which supports its role in epigenetic regulation and chemoprevention. Additionally, curcumin influences cellular redox balance and induces apoptosis in cancer cell lines.
Planta Analytica provides high-purity curcumin together with related standards — desmethoxycurcumin and bisdesmethoxycurcumin. These standards enable accurate profiling of curcuminoids in botanical extracts. They support advanced applications in phytochemistry, quality control, and pharmacognosy.
References
Withanoside IV and its active metabolite
Compound Details
| CAS | 458-37-7 |
|---|---|
| Molecular Weight | 368.4 |
| Chemical Formula | C₂₁H₂₀O₆ |
| IUPAC | (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione |
| Synonyms | Diferuloylmethane |
| SMILES | COC1=C(C=CC(=C1)/C=C/C(=O)CC(=O)/C=C/C2=CC(=C(C=C2)O)OC)O |
| Storage Temperature | Below −18°C |
| Storage Conditions | Dry, freezer |
$3.50 - $4.95 / milligram
| Range (milligram) | Price ($/milligram) |
|---|---|
| 20 - 49 milligram | $4.95 / milligram |
| 50 - 249 milligram | $4.25 / milligram |
| 250 - 499 milligram | $3.95 / milligram |
| 500 - 1000 milligram | $3.50 / milligram |
Technical Support
Product information is from published literature. Due to the nature of scientific experimentation, results or specific product application may vary (e.g., selectivity, detector response). If you have questions about the product, its application, and associated analytics, please contact our technical support team.
Product Use Disclaimer
Products are sold as laboratory reference materials, to be used for diagnostic and in vivo testing. The samples are not certified for veterinary or human use.



