Sennoside A

CAS: 81-27-6
CAT: 5093

Abstract

Sennoside A (CAS 81-27-6) is isolated from Senna (Cassia species), a popular herbal laxative that is available without a prescription. Studies have shown senna stimulates the colon to induce contractions and decrease water absorption, these effects would provide relief from constipation. Sennosides have been reviewed for treatment of constipation in children and the elderly alone or in combination with sorbitol or lactulose. Sennosides have many bioactive components and the product is usually safe and well tolerated, but can lead to adverse events including clinically apparent liver injury when used in high doses beyond the recommended period.

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Withanoside IV and its active metabolite

Category:

Compound Details

CAS

81-27-6

Molecular Weight

862.7 g/mol

Chemical Formula

C₄₂H₃₈O₂₀

IUPAC

9-[2-carboxy-4-hydroxy-10-oxo-5-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid

Synonyms

N/A

SMILES

C1=CC2=C(C(=C1)OC3C(C(C(C(O3)CO)O)O)O)C(=O)C4=C(C2C5C6=C(C(=CC=C6)OC7C(C(C(C(O7)CO)O)O)O)C(=O)C8=C5C=C(C=C8O)C(=O)O)C=C(C=C4O)C(=O)O

Purity

95%+

Storage Temperature

Below −18°C

Storage Conditions

Under N₂, Freezer, Dark

Product Documents

Certificates of Analysis

Safety Data Sheets

PRICE ON REQUEST

Range (milligram)Price ($/milligram)
5 - 24 milligramPrice on Request
25 - 99 milligramPrice on Request
100 - 249 milligramPrice on Request
250 - 499 milligramPrice on Request
500 - 1000 milligramPrice on Request
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Technical Support

Product information is from published literature. Due to the nature of scientific experimentation, results or specific product application may vary (e.g., selectivity, detector response). If you have questions about the product, its application, and associated analytics, please contact our technical support team.

Product Use Disclaimer

Products are sold as laboratory reference materials, to be used for diagnostic and in vivo testing. The samples are not certified for veterinary or human use. 

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