Progoitrin – CAS 585-95-5

Progoitrin (CAS 585-95-5) is in a group of sulfur-containing glycosides called glucosinolates. Glucosinolates are mainly present in cruciferous or brassica vegetables, such as broccoli, cabbage, cauliflower, rapeseed, and mustard. The sulfur group results in the pungent smell. Research indicates the beneficial effects of glucosinolates. These effects include regulatory functions in inflammation, stress response, phase I metabolism, antioxidant activities, and antimicrobial properties.

Progoitrin is isolated from cabbage, brussels sprouts, kale, mustard, rutabaga, kohlrabi, spinach, and cauliflower. This glucosinolate is inactive until it is hydrolyzed into goitrin, which is named for its antithyroid activity. Goitrin inhibits the thyroid hormones, thyroxine and triiodothyronine.

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