Amino avermectin B1a

CAS: 121064-68-4
CAT: 10072

Abstract

Amino Avermectin B1a is a high purity reference standard used in residue analysis, method development, and environmental fate studies. As a member of the avermectin family of 16 membered macrocyclic lactones, it provides a relevant comparator for avermectin and emamectin profiling programs.

Produced through Streptomyces avermitilis fermentation, the compound retains the natural macrocyclic scaffold with a 4 double prime amino, 4 double prime deoxy substitution on the sugar group. This modification makes it useful for tracking transformation pathways and confirming impurity identities in complex matrices.

Its structural similarity to commercial avermectins supports laboratories developing selective and reliable analytical methods. In invertebrates, avermectin class compounds act on glutamate gated chloride channels, increasing chloride influx and disrupting neurotransmission. This mode of action underlines the need for accurate profiling of related compounds in environmental evaluations.

Related avermectin and emamectin standards, impurities, and metabolites are available to support QC and comparability studies. View the related products here.

Withanoside IV and its active metabolite

Compound Details

CAS

121064-68-4

Molecular Weight

872.1 g/mol

Chemical Formula

C₄₈H₇₃NO₁₃

IUPAC

(10E,14E,16E,22Z)-(1R,4S,5′S,6S,6′R,8R,12S,13S,20R,21R,24S)-6′-[(S)-sec-butyl]-21,24-dihydroxy-5′,11,13,22-tetramethyl-2-oxo-(3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene)-6-spiro-2′-(5′,6′-dihydro-2′H-pyran)-12-yl

Synonyms

AB1

SMILES

C/C([C@@H](O[C@]1(C[C@@H]([C@H]([C@@H](O1)C)O[C@]2(C[C@@H]([C@@H]([C@@H](O2)C)N)OC)[H])OC)[H])[C@H](/C=C/C=C3CO[C@]4([C@@]\3([C@@]([H])(C=C([C@H]4O)C)C(O[C@H](C[C@]5(O6)O[C@]([C@@]([H])(C)CC)([C@H](C=C5)C)[H])C7)=O)O)[H])C)=C\C[C@]76[H]

Purity

95%+

Storage Temperature

Below −18°C

Storage Conditions

Dry, freezer

Product Documents

Certificates of Analysis

Safety Data Sheets

PRICE ON REQUEST

Range (milligram)Price ($/milligram)
5 - 24 milligramPrice on Request
25 - 99 milligramPrice on Request
100 - 249 milligramPrice on Request
250 - 1000 milligramPrice on Request
Product Price

Technical Support

Product information is from published literature. Due to the nature of scientific experimentation, results or specific product application may vary (e.g., selectivity, detector response). If you have questions about the product, its application, and associated analytics, please contact our technical support team.

Product Use Disclaimer

Products are sold as laboratory reference materials, to be used for diagnostic and in vivo testing. The samples are not certified for veterinary or human use. 

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