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Hastatoside – CAS 50816-24-5

Abstract

Hastatoside (CAS 50816-24-5) is an iridoid glycoside isolated from Vervain/Verbena (Verbena officinalis). Herbal tea made from Verbena has been utilized for the treatment of insomnia and other nervous conditions. The major iridoid components in Verbena are hastatoside and verbenalin. The major polyphenol component in Verbena is verbascoside. Research on the sleep-promoting activity of these three compounds indicated that both iridoid components are major sleep-promoting compounds of V. officinalis.

Hastatoside has been studied for its efficacy of inhibiting liver fibrosis. The findings suggest that it can bind to GSK-3β while inhibiting the GSK-3β downstream effector expression of β-catenin. This results in inhibiting of the activation and proliferation of HSCs, preventing the development of liver fibrosis. (Taotao Ma et. al.)

Category:

Compound Details

CAS

50816-24-5

Molecular Weight

404.37

Chemical Formula

C17H24O11

IUPAC

methyl (1S,4aR,7S,7aR)-4a-hydroxy-7-methyl-5-oxo-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,6,7,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate

Synonyms

5-Hydroxyverbenalin

SMILES

CC1CC(=O)C2(C1C(OC=C2C(=O)OC)OC3C(C(C(C(O3)CO)O)O)O)O

Purity

95%+

Storage Temperature

Below -18 degrees C

Storage Conditions

Dry, freezer

Product Documents

Product Use Disclaimer

Products are sold as laboratory reference materials, to be used for diagnostic and in vivo testing. The samples are not certified for veterinary or human use. 

$12.00 - $17.50 / milligram

Range (milligram)Price ($/milligram)
5 - 24 milligram$17.50 / milligram
25 - 99 milligram$16.00 / milligram
100 - 249 milligram$14.50 / milligram
250 - 499 milligram$13.00 / milligram
500 - 1000 milligram$12.00 / milligram
Product Price
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Technical Support

Product information is from published literature. Due to the nature of scientific experimentation, results or specific product application may vary (e.g., selectivity, detector response). If you have questions about the product, its application, and associated analytics, please contact our technical support team.

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