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Deguelin – CAS 522-17-8

Deguelin 522-17-8

Abstract

Deguelin (CAS 522-17-8) is a derivative of rotenone. Both are compounds classified as rotenoids of the flavonoid family and are naturally occurring insecticides. They can be produced by extraction from several plant species belonging to three genera of the legume family, Fabaceae: Lonchocarpus, Derris, or Tephrosia. Deguelin has been studied for its possible anti-cancer activity. It has shown to inhibit growth of pre-cancerous and cancerous cells, primarily in lung cancer.

Deguelin has also been studied for it negative effects and possibility as a cause of Parkinson’s disease. There was no direct correlation with compound, however, there were more general indications of inflammatory effects related to overexposure to irritants.

For other common insecticides, see our other agrochemical reference standards.

Category:

Compound Details

CAS

522-17-8
Molecular Weight

394.4
Chemical Formula

C23H22O6
IUPAC

(1S,14S)-17,18-dimethoxy-7,7-dimethyl-2,8,21-trioxapentacyclo[12.8.0.03,12.04,9.015,20]docosa-3(12),4(9),5,10,15,17,19-heptaen-13-one
Synonyms

(-)-Deguelin
SMILES

CC1(C=CC2=C(O1)C=CC3=C2OC4COC5=CC(=C(C=C5C4C3=O)OC)OC)C
Purity

95%+
Storage Temperature

Below -18 degrees C
Storage Conditions

Dry, freezer

Product Documents

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Products are sold as laboratory reference materials, to be used for diagnostic and in vivo testing. The samples are not certified for veterinary or human use. 

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