Curcumin

Curcumin (CAS 458-37-7) is a principal curcuminoid derived from Curcuma longa, the botanical source of turmeric. As a diarylheptanoid, curcumin is structurally defined as diferuloylmethane, comprising two ferulic acid units connected by a seven-carbon linker. This configuration imparts its characteristic yellow pigmentation and underpins its diverse pharmacological profile.

Curcumin is widely recognized for its anti-inflammatory and antioxidant properties, making it a valuable standard in research focused on arthritis, osteoarthritis, and chronic inflammatory conditions. It modulates key molecular targets such as NF-κB, COX-2, and iNOS, and inhibits histone acetyltransferase activity, positioning it as a potent agent in epigenetic regulation and chemoprevention. Its ability to influence cellular redox states and induce apoptosis in cancer cell lines further supports its relevance in oncology and molecular biology studies.

Planta Analytica supplies high-purity curcumin along with structurally related standards including desmethoxycurcumin and bisdesmethoxycurcumin, enabling comprehensive profiling of curcuminoid content in botanical extracts and supporting advanced analytical applications in phytochemistry and pharmacognosy. Find the additional targets here.