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Cimicifugoside H-1

Cimicifugoside H-1 CAS 163046-73-9

Abstract

Cimicifugoside H-1 (CAS 163046-73-9) and Cimicifugoside H-2 are natural triterpene glycosides found in the roots/rhizomes of black cohosh (Cimicifuga racemosa). Black cohosh was traditionally used for the treatment of menopausal symptoms, menstrual cramps, and other conditions. Studies have shown it can be successfully used in mammary cancer patients without having adverse effects on breast tissue. These are not estrogenic compound, they have a different pharmacological action which positively influence postmenopausal syndrome. Studies have shown that these compounds decrease the proliferative action of estrogen, and were able to alter the growth of hormone-dependent mammary cancer cells. 

Cimicifugoside H-1 and Cimicifugoside H-2 are two of the five main cimicifugosides. These cimicifugosides have gained attention in recent years due to their potential therapeutic effects and roles in drug development.

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Compound Details

CAS

163046-73-9
Molecular Weight

616.792
Chemical Formula

C35H52O9
IUPAC

(1S,3R,6S,8R,12R,15R,16R,18S)-15-[(2R)-4-[(2R)-3,3-dimethyloxiran-2-yl]-4-oxobutan-2-yl]-18-hydroxy-7,7,12,16-tetramethyl-6-, [(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxypentacyclo[9.7.0.01,3.03,8.012,16]octadec-10-en-14-one
Synonyms

Cimicifugoside H 1, C3LF0ZYD3S, Cimifugoside H-1
SMILES

CC(CC(=O)C1C(O1)(C)C)C2C(=O)CC3(C2(CC(C45C3=CCC6C4(C5)CCC(C6(C)C)OC7C(C(C(CO7)O)O)O)O)C)C
Purity

98%+
Storage Temperature

Below -18 degrees C
Storage Conditions

Dry, freezer

Product Documents

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Products are sold as laboratory reference materials, to be used for diagnostic and in vivo testing. The samples are not certified for veterinary or human use. 

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Product information is from published literature. Due to the nature of scientific experimentation, results or specific product application may vary (e.g., selectivity, detector response). If you have questions about the product, its application, and associated analytics, please contact our technical support team.

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