Brucine

Abstract

Brucine (CAS 357-57-3) is a monoterpenoid indole alkaloid and an organic heteroheptacyclic compound. It appears as a white crystalline solid and is a natural product found in Strychnos axillaris, Strychnos ignatii, and other organisms. It is usually used as an anti-inflammatory and analgesic drug to relieve arthritis and traumatic pain.  Brucine is an alkaloid closely related to strychnine, and although less toxic, the narrow therapeutic window greatly limits its ability to be used in pharmacological applications. Brucine intoxication is uncommon as it occurs with strychnine but is significantly less toxic.

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Compound Details

CAS

357-57-3

Molecular Weight

394.5

Chemical Forumla

C23H26N2O4

IUPAC

(4aR,5aS,8aR,13aS,15aS,15bR)-10,11-dimethoxy-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinolin-14-one

Synonyms

Brucinum

SMILES

COC1=C(C=C2C(=C1)C34CCN5C3CC6C7C4N2C(=O)CC7OCC=C6C5)OC

Purity

95%+

Storage Temperature

Below -18 degrees C

Storage Conditions

Dry, freezer

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Products are sold as laboratory reference materials, to be used for diagnostic and in vivo testing. The samples are not certified for veterinary or human use. 

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Product information is from published literature. Due to the nature of scientific experimentation, results or specific product application may vary (e.g., selectivity, detector response). If you have questions about the product, its application, and associated analytics, please contact our technical support team.

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