Procyanidin B3 – CAS 23567-23-9

Abstract

Procyanidins are proanthocyanidins formed from (+) catechin and (-) epicatechin. Procyanidins can be categorized into A-type and B-type, depending on the nature of the interflavan bonds. B-type procyanidins have a single interflavan bond. A-type procyanidins have not only one interflavan bond, but also a second interflavanoid bond. The most common B-type procyanidins are B1, B2, B3, and B4. Procyanidin B3 (CAS 23567-23-9) is a catechin-(4β→8)-catechin dimer. It is commonly isolated from cinnamon, cocoa, and apples.

Androgen receptor acetylation is critical for prostate cancer cell growth. Thus, the development of histone acetyltransferase (HAT) inhibitors has been a therapeutic goal. Procyanidin B3 is reported to possess the highest anti-HAT activity among the catechin derivatives.

You can find additional procyanidin reference standards here.

Categories: Apple PACs, Cinnamon PACs, Cocoa PACs, Procyanidins (PACs)

Compound Details

CAS	23567-23-9
Molecular Weight	578.52
Chemical Formula	C30H26O12
IUPAC	(2R,3S)-2-(3,4-dihydroxyphenyl)-8-[(2R,3S,4S)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-4-yl]-3,4-dihydro-2H-chromene-3,5,7-triol
Synonyms	Catechin-(4α→8)-catechin
SMILES	C1C(C(OC2=C1C(=CC(=C2C3C(C(OC4=CC(=CC(=C34)O)O)C5=CC(=C(C=C5)O)O)O)O)O)C6=CC(=C(C=C6)O)O)O
Purity	95%+
Storage Temperature	Below -18 degrees C
Storage Conditions	Dry, freezer

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