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Presence of 1-(2,4,6-trihydroxyphenyl)-3-(3,4-dihydroxyphenol)-propanol-2 in Grape Seed Extract indicates involvement of anaerobic bacteria in the production stages

AbstractForty six samples of Grape Seed Extract from domestic and international producers were analyzed chromatographically by RP HPLC and by NMR to evaluate chemical diversity. In six samples a prominent peak of an unknown phenolic substance reaching up to 2 % was found and was subsequently attributed to 1-(2,4,6-trihydroxyphenyl)-3-(3,4-dihydroxyphenol)propanol-2 (TDP). TDP is known to be produc... READ MORE

Four A-type procyanidin trimers are main flavanol components of Cinnamomum burmanii

AbstractCinnamon spice is derived from bark of several Cassia and Cinnamomum genera. Depending on the origin, there are distinctive differences between composition of the water-soluble procyanidins, which are mainly consisting of A-type procyanidins, attributed with anti-diabetic activity. Trimers are dominant group, while tetramers are at ca. 20% of the trimer content and other oligomeric DPs con... READ MORE

Honey, Bees, and Hepatotoxis Alkaloid Echimidine

AbstractEchimidine (1) is the main pyrrolizidine alkaloid of Echium plantagineum L, (Jane’s Salvation, Patersons Curse), endemic to Australia[1]. The plant is a great attractant for bees and as a result echimidine finds its way into honey. Because of its hepatotoxicity, echimidine became a target of new EU regulation requiring testing of imported honey. Under normal RP HPLC conditions echimidine... READ MORE

BIOLOGICAL ACTIVITIES OF TRITERPENES ISOLATED FROM THE MEDICINAL MUSHROOM GANODERMA LUCIDUM

AbstractMethanol extract of Ganoderma lucidum subjected to fractionation on silica gel medium pressure column afforded over 40 fractions. Further fractionation was carried out using Centrifugal Partition Chromatography (FCPC Rousselet Robatel, France), in the hexane-EtOAc-MeOH-Water systems adjusted for the polarity of each fraction. Some isolates were further purified by preparative HPLC. Methyl ... READ MORE

Fractionation of Cocoa Procyanidins by Degree of Polymerization

Proanthocyanidins (procyanidins) derived from natural products such as cocoa, cranberries, peanuts and many other dietary products, have become a popular field of research in neutraceuticals. Procyanidins are composed of varying degrees of polymerization of primarily catechin and epicatechin, and occur naturally in the hundreds.Although there has been increasing interest in the compounds which hav... READ MORE

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